Do you care about your cardiovascular health? If so, then you’ll be interested in the powerful impact of Vitamin K2 as MK-7 on arterial calcification. This micronutrient has been found to play an important role in reducing the risk of heart attack and stroke. In this article, we will discuss the science behind this nutrient, as well as its potential benefits for maintaining a healthy heart and arteries.
Vitamin K2 is a fat-soluble vitamin that belongs to a group of compounds known as “vitamin K”. It is often referred to as menaquinone or menatetrenone, and the two most common forms are MK-4 and MK-7. Studies have shown that Vitamin K2 plays an important role in helping to keep calcium in the bones where it belongs, thus preventing it from being deposited in the arteries.
Vitamin K2 has been proven to help reduce arterial calcification, ultimately improving overall cardiovascular health. By understanding how Vitamin K2 works within our bodies and how it can benefit us, we can make informed decisions regarding our health and nutrition choices. In this article, we will explore the science behind Vitamin K2 and its effects on arterial calcification.
Table of Contents
Definition Of Vitamin K2
Vitamin K2 is a fat-soluble vitamin that the human body needs for many essential functions. It’s found in some foods and can also be taken as a supplement. Vitamin K2, also known as menaquinone (MK-7), is important for blood clotting, bone health, and cardiovascular health. It helps to regulate calcium levels in the body, which can help prevent arterial calcification and other cardiovascular problems.
Vitamin K2 is found naturally in some foods such as cheese, eggs, poultry, and organ meats. However, it’s not widely available in food sources so taking supplements is recommended for people who don’t get enough through their diet. Taking vitamin K2 as MK-7 has been shown to be more effective than taking other forms of vitamin K supplements because it stays in the body longer and has higher bioavailability.
Studies have shown that taking vitamin K2 as MK-7 can reduce arterial calcification by up to 60%. This could potentially reduce the risk of cardiovascular disease and stroke by preventing calcium buildup in arteries. Additionally, studies have linked low levels of vitamin K2 with increased risk of osteoporosis and bone fractures. These findings suggest that taking vitamin K2 as MK-7 could help improve overall bone health and reduce the risk of fractures.
Role Of Mk-7 In The Body
Vitamin K2 as MK-7 has a substantial impact on arterial calcification. MK-7 is a form of vitamin K that helps to activate proteins involved in calcium metabolism, including osteocalcin and matrix Gla protein (MGP). Osteocalcin is responsible for binding calcium to the bones and MGP acts as an inhibitor of mineralization of soft tissues, such as the arterial walls. By activating these proteins, MK-7 helps to prevent arterial calcification.
Studies have shown that taking supplemental MK-7 can reduce the levels of arterial calcification significantly. For instance, one study found that supplementing with 180 mcg per day reduced levels of arterial calcification by up to 50%. Additionally, higher doses (360mcg) may result in even greater reductions in arterial calcification. Moreover, regular supplementation with MK-7 can also help reduce the risk of cardiovascular disease.
The impact of vitamin K2 as MK-7 on arterial calcification demonstrates its important role in promoting healthy heart function and overall cardiovascular health. As such, it is recommended that individuals consider supplementing with MK-7 daily to ensure they are getting enough of this important nutrient and reaping the full benefits it offers.
Sources Of Mk-7
MK-7 is a form of vitamin K2 that has been found to have positive effects on arterial calcification. It is naturally found in some foods, such as natto, a traditional Japanese dish, and in certain fermented foods like cheese. In addition, it is also available in supplement form.
The main source of MK-7 is natto, which is made from soybeans fermented with the bacterium Bacillus subtilis. Natto contains high levels of MK-7 compared to other food sources, providing about 100 micrograms (mcg) per 100 grams (g). Additionally, some other fermented foods like hard cheeses contain small amounts of MK-7.
MK-7 supplements are also available as tablets or capsules and typically provide between 45 mcg and 200 mcg of MK-7 per serving. They are a convenient way to get higher doses of MK-7 than what can be obtained from food sources alone. For example, taking two servings of a supplement that provides 150 mcg per serving would result in 300 mcg of MK-7 total.
Benefits Of Vitamin K2 As Mk-7
Vitamin K2 as MK-7 has been found to have numerous benefits for the body. Studies have suggested that it can help reduce arterial calcification and improve vascular health. It plays a role in activating proteins that are essential for calcium metabolism, which helps to prevent calcium from depositing in the blood vessels and arteries. Moreover, Vitamin K2 as MK-7 has also been linked to improved bone mineral density and reduced risk of fractures.
In addition to its effects on arterial health, Vitamin K2 as MK-7 may also have other beneficial effects on human health. Its antioxidant properties make it useful in reducing oxidative damage caused by free radicals. Furthermore, studies suggest that it may help reduce inflammation and improve metabolic control, which could potentially lead to better overall health.
Vitamin K2 as MK-7 is found naturally in certain foods such as natto, a traditional Japanese food made from fermented soybeans, and certain animal sources like egg yolks and liver. It is also available as a dietary supplement in both liquid and capsule form. For those looking to get the most out of their Vitamin K2 intake, taking a supplement may be an effective way of obtaining the required amount of this vitamin each day.
No matter how you choose to consume it, Vitamin K2 as MK-7 can play an important role in improving your overall health by helping protect against various diseases associated with aging such as heart disease and osteoporosis. With its numerous potential benefits for both arterial health and overall well-being, incorporating this vitamin into your diet can be an important step towards better health outcomes.
Potential Risks And Side Effects
The potential risks and side effects associated with vitamin K2 as MK-7 supplementation are largely unknown. Studies have not been conducted to assess the long-term effects of taking high doses of this supplement, so it is difficult to know if there are any serious adverse effects. However, some minor side effects such as nausea and stomach upset have been reported. Additionally, people who take too much of this supplement may be at risk for developing an imbalance in calcium levels that could lead to other health complications.
In terms of arterial calcification, studies suggest that vitamin K2 as MK-7 may help reduce calcification in the arteries when taken in recommended dosages. However, higher doses may actually increase calcification or contribute to blockages in the arteries. For this reason, it is important to consult with a healthcare professional before taking any form of this supplement, especially if you already have cardiovascular disease or risk factors for it.
Overall, there is still more research needed on the potential risks and side effects associated with vitamin K2 as MK-7 supplementation. It is important to speak to your doctor before beginning any new supplement regimen and follow the dosage instructions provided by the manufacturer carefully. Taking too much vitamin K2 as MK-7 can be dangerous and should always be done under medical supervision.
Absorption And Metabolism
Vitamin K2 as MK-7 is absorbed in the small intestine and then metabolized in the liver. It is then incorporated into various proteins, which are responsible for its biological activity. Vitamin K2 as MK-7 has been shown to be more bioavailable than other forms of vitamin K, such as vitamin K1 or MK-4. Studies have demonstrated that it is rapidly absorbed, with peak plasma concentrations occurring within four hours of ingestion. The bioavailability of MK-7 appears to be independent of food intake and dose size.
Once it is absorbed and metabolized, vitamin K2 as MK-7 circulates throughout the body and can be transported to target tissues where it can modulate calcium metabolism. It has been shown to interact with proteins involved in calcium transport and deposition in bones, thus reducing calcification of arteries. Additionally, studies have found that it may also reduce inflammation and oxidative stress, both of which are associated with increased risk for cardiovascular disease.
The exact mechanism by which vitamin K2 as MK-7 affects arterial calcification remains unclear; however, its ability to influence calcium metabolism suggests that it could play a role by inhibiting calcification processes in the vascular system. Given this potential protective effect, further research is needed to explore the full impact of this form of vitamin K on arterial calcification.
Recommended Dosage
Moving on, it is important to consider the recommended dosage for Vitamin K2 as MK-7 in order to maximize its impact on arterial calcification. Generally, studies have shown that dosages of 45 mcg/day or higher are necessary for optimal effects. In comparison, the average Western diet provides only 10-20 mcg/day of Vitamin K2 as MK-7. To supplement this amount, many health professionals recommend taking a multivitamin containing at least 45 mcg/day of MK-7. Additionally, some studies suggest that doses up to 180 mcg/day may be beneficial for those with more severe arterial calcification.
When taking a supplement containing Vitamin K2 as MK-7, it is also important to choose a product with reliable quality and potency. As with any dietary supplement, look for one that has been tested by an independent third party and carries the seal of approval from a reputable organization such as USP or NSF International. Furthermore, always follow the directions provided on the label and talk to your doctor before beginning any new regimen or increasing an existing dosage.
Finally, it is essential to understand that Vitamin K2 as MK-7 plays an important role in maintaining healthy arteries and preventing calcification. As such, it should be taken in conjunction with other lifestyle modifications like exercising regularly and eating a nutritious diet in order to maximize its effectiveness in reducing arterial calcification risk.
Interactions With Other Medications
Vitamin K2 as MK-7 has been shown to interact with certain medications. Warfarin, a blood thinner, may be affected by vitamin K2 as MK-7. Warfarin is used to reduce the risk of stroke in people with heart disease and to slow or prevent the buildup of plaque in arteries. It is important that those taking warfarin monitor their clotting times closely when taking vitamin K2 as MK-7. Additionally, statin drugs often prescribed for cholesterol reduction can also be impacted by Vitamin K2 as MK-7. Studies suggest that taking Vitamin K2 as MK-7 while on statins may lead to better cholesterol levels than those achieved with just statins alone. Finally, Vitamin K2 as MK-7 has been found to interact with nonsteroidal anti-inflammatory drugs (NSAIDs). Taking these drugs alongside Vitamin K2 as MK-7 could potentially increase the risk of bleeding. It is recommended that patients consult their physician before taking any other medications along with Vitamin K2 as MK-7.
Research Studies On Arterial Calcification
Recent studies have investigated the impact of vitamin K2 as MK-7 on arterial calcification. One study found that MK-7 supplementation was associated with decreased aortic calcification in those with chronic kidney disease. Another study showed that people with the highest levels of MK-7 had significantly lower aortic calcium concentrations compared to those with the lowest levels. Additionally, another study observed that MK-7 supplementation was linked to less coronary artery calcification in those with coronary artery disease.
There has also been research into the effects of vitamin K2 as MK-7 and its potential to reduce vascular stiffness. One randomized controlled trial found that after 18 months, participants who were given a daily dose of 180 mcg of MK-7 had significantly lower pulse wave velocity than those given placebo, suggesting that it can help improve vascular health. Other studies have shown similar results, demonstrating that supplementing with vitamin K2 may be beneficial for maintaining healthy arteries and reducing risk factors for cardiovascular diseases.
Overall, these findings indicate that supplementing with vitamin K2 as MK-7 may help reduce arterial calcification and improve vascular health in at risk populations. This suggests that further research is needed to better understand how this vitamin could be used to prevent or treat cardiovascular diseases in the future.
Impact On Cardiovascular Health
The impact of vitamin K2 as MK-7 on cardiovascular health has been studied extensively. This type of vitamin K2 is thought to support healthy arterial calcification, which may reduce an individual’s risk of developing cardiovascular disease. Studies have shown that this form of vitamin K2 may help to reduce the oxidation of low-density lipoprotein (LDL) cholesterol, a major contributor to the development of heart disease. In addition, research suggests that it may also help to reduce inflammation in the arteries and improve overall circulation.
Vitamin K2 as MK-7 has also been found to increase the production of matrix Gla protein (MGP), which is responsible for keeping calcium out of the walls of the arteries and veins. By aiding in MGP production, MK-7 helps protect against arterial stiffness and calcification, both known risk factors for cardiovascular disease. Additionally, studies suggest that this form of vitamin K2 can promote healthy blood clotting by activating proteins involved in clot formation and reducing clotting time.
Overall, evidence suggests that adequate intake of vitamin K2 as MK-7 may be beneficial for cardiovascular health by reducing LDL oxidation and arterial calcification, increasing MGP production, and promoting healthy blood clotting. It is important to note that more research is needed before definitive conclusions can be made regarding the effects of this form of vitamin K2 on cardiovascular health.
Frequently Asked Questions
Who Should Take Vitamin K2 As Mk-7?
Who should take Vitamin K2 as MK-7? This is an important question that must be considered when looking at the impact of Vitamin K2 as MK-7 on arterial calcification. Generally, it is recommended that those with a higher risk of developing calcified arteries or heart disease consider taking a supplement of vitamin K2 as MK-7. This includes people who are elderly, have high levels of cholesterol and triglycerides, or have diabetes. It may also be beneficial for those who are following a low-calcium diet or have had a stroke in the past.
Vitamin K2 as MK-7 is found naturally in some foods such as cheese and eggs, but it can also be taken in supplement form. Research has shown that taking vitamin K2 supplements can help reduce the risk of developing arterial calcification by up to 60%. It also helps increase bone mineral density which can lower the risk of fractures. Additionally, vitamin K2 has been linked to improved cardiovascular health and better blood vessel function.
In order to reap the full benefits of Vitamin K2 as MK-7, it is important to speak with your doctor first before starting any supplement program. They will be able to evaluate your individual needs and provide advice on the right dosage for you. Additionally, they may suggest lifestyle changes such as increasing physical activity, reducing saturated fats and eating more fruits and vegetables. Taking all these factors into consideration will ensure you get the most out of your vitamin K2 supplementation while minimizing any potential risks associated with it.
Vitamin K2 as MK-7 has many potential health benefits for those at risk of arterial calcification and related conditions like heart disease or osteoporosis. While there are no guarantees regarding its effectiveness, consulting with a healthcare professional about its use could lead to a better understanding of how it might help improve one’s overall health outcomes.
What Is The Difference Between Vitamin K2 And Vitamin K1?
Vitamin K is a fat-soluble vitamin that plays an important role in blood clotting and bone health. There are two forms of Vitamin K: Vitamin K1 and Vitamin K2. Both forms are essential for preventing excessive bleeding, but they differ in their function and how they are obtained.
Vitamin K1, also known as phylloquinone, is obtained through dietary sources such as leafy green vegetables, broccoli, and Brussels sprouts. It is primarily responsible for helping the body with blood clotting. On the other hand, Vitamin K2 (also known as menaquinones) can be produced by certain bacteria found in the digestive tract or obtained from animal sources like organ meats or egg yolks. It helps to activate proteins that bind calcium and deposit it into bones to strengthen them.
The primary difference between these two types of Vitamin K is that Vitamin K1 is found mainly in plants while Vitamin K2 is found mainly in animal sources. Additionally, while both vitamins help regulate blood clotting, only Vitamin K2 helps with calcium binding to bones which makes it more beneficial for overall bone health than its counterpart. Therefore, those who have a diet limited in animal products may need to supplement their diet with Vitamin K2 if they want to get enough of this important nutrient.
Vitamin K2 can be especially beneficial for people at risk of cardiovascular disease or osteoporosis due to its ability to help regulate calcium levels in the body which can reduce calcification of arterial walls and lessen the risk of developing these conditions. For this reason, those who are at risk should consider adding a supplement containing vitamin k2 mk-7 to their daily routine.
Are There Any Drug Interactions Associated With Vitamin K2 As Mk-7?
Are there any drug interactions associated with Vitamin K2 as MK-7? This is a valid question to ask when considering supplementation of Vitamin K2 as MK-7. It’s important to understand potential drug interactions when taking any supplement, and Vitamin K2 as MK-7 is no exception.
Vitamin K2 as MK-7 is a form of vitamin K that has been linked to reducing the risk of arterial calcification. However, there are a few drugs that may interact with it, and so it’s important to take this into account before using it. For example, some anticoagulants such as warfarin can interact with Vitamin K2 as MK-7 and reduce its effectiveness. It’s also important to note that people taking aspirin are advised not to use Vitamin K2 as MK-7 because it can increase the risk of bleeding. Additionally, certain antibiotics such as tetracycline can also interfere with the absorption of Vitamin K2 as MK-7.
It’s important to speak with your doctor or pharmacist before taking any supplements that may interact with medications you’re already taking. There may be alternative therapies or strategies available in order to minimize any potential drug interactions while still obtaining the health benefits associated with Vitamin K2 as MK-7 supplementation. Furthermore, it’s generally recommended to take lower doses when combining supplements and medications in order to reduce the risk of adverse reactions or interactions occurring between them.
In summary, there are a few medications that have been known to interact with Vitamin K2 as MK-7 supplementation, including anticoagulants, aspirin and some antibiotics. Therefore, it is essential for individuals who are currently taking any medication or supplement to discuss their options with their healthcare provider prior to starting treatment in order to ensure safe use and maximize health benefits.
Is There Any Evidence To Suggest That Vitamin K2 As Mk-7 Can Prevent Arterial Calcification?
The current H2 is whether there is evidence to suggest that Vitamin K2 as MK-7 can prevent arterial calcification. This question has been asked more and more frequently in recent years due to the growing awareness of the importance of Vitamin K2 in promoting good health. The answer to this question is: yes, there does appear to be some evidence to suggest that Vitamin K2 as MK-7 may be beneficial for preventing arterial calcification.
First, it is important to understand what exactly Vitamin K2 as MK-7 is. It is a form of vitamin K that helps with blood clotting and bone formation. In addition, it can help reduce calcium deposits in the arteries, which can lead to hardening of the arteries and other cardiovascular problems. Furthermore, studies have shown that supplementing with Vitamin K2 as MK-7 can help reduce levels of artery-clogging lipids in people with high cholesterol levels.
Second, there are numerous studies that have looked at the effects of Vitamin K2 as MK-7 on arterial calcification. These studies have found that supplementing with Vitamin K2 as MK-7 can reduce calcium deposits in arteries and therefore decrease the risk of having a heart attack or stroke caused by these deposits. A study conducted on rats showed that supplementing with Vitamin K2 as MK-7 significantly decreased calcium accumulation in their aortas after only three months of supplementation. Additionally, another study showed that supplementing with Vitamin K2 as MK-7 could reduce vascular stiffness and improve overall heart health markers in people aged 65 and older who had higher levels of arterial calcification.
Finally, although there is evidence suggesting that supplementing with Vitamin K2 as MK-7 may help reduce arterial calcification, it should not be used for treating any existing cardiovascular conditions without consulting your physician first. In addition, due to its blood clotting properties, it may increase the risk of bleeding if taken along with certain medications or supplements such as aspirin or warfarin. Therefore, it’s advisable to speak with your healthcare provider before starting any new supplement regimen including Vitamin K2 as MK-7.
Are There Any Dietary Sources Of Vitamin K2 As Mk-7?
When it comes to vitamin K2 as MK-7, one of the most important questions people need to ask is: are there any dietary sources? This is especially relevant for those looking to prevent arterial calcification, as Vitamin K2 as MK-7 has been found to have a positive impact on this condition. Thankfully, there are a few dietary sources of Vitamin K2 as MK-7 that can be easily accessed.
The most common source of Vitamin K2 as MK-7 is natto, a traditional Japanese food made from fermented soybeans. Natto typically contains more than 100 μg of Vitamin K2 per 100 grams, so it’s an excellent natural source of the nutrient. Other sources include eggs and some cheeses such as Gouda and Brie. Additionally, certain types of mushrooms contain high levels of Vitamin K2, such as maitake and shiitake mushrooms.
For those who would prefer to supplement their diet with Vitamin K2, some manufacturers produce supplements containing MK-7 in pill form or liquid drops, which may be easier to take in larger doses than the natural dietary sources mentioned above. It’s important to note that while these supplements may offer higher concentrations of the nutrient than what you’d find in dietary sources, they may also cause side effects if taken in high doses. As always, it’s best to consult with your doctor before taking any supplements or making drastic changes to your diet.
Clearly, there are several options available for those looking for dietary sources of Vitamin K2 as MK-7. Whether you choose natto or another natural source or opt for a supplement instead, make sure you talk with your healthcare provider first before adding this nutrient into your regimen.
Conclusion
In conclusion, Vitamin K2 as MK-7 can be an effective supplement for those who have a vitamin K deficiency or are at risk of developing arterial calcification. It is important to note the difference between Vitamin K1 and K2, as well as any potential drug interactions, before taking this supplement. While there is scientific evidence to suggest that Vitamin K2 as MK-7 can help prevent arterial calcification, it is best to speak with a healthcare professional before incorporating it into one’s routine. Additionally, there are dietary sources of Vitamin K2 such as natto, egg yolks, aged cheese, and liver which may provide some benefit. As always, it is important to consult with your doctor before making any changes to your diet or supplementation regimen.
References: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8483258/
